Date: Thursday, 20 May 2021
Time: 11:30M-12.30PM EST
Venue: WebinarREGISTER HERE
In this seminar, Dr. Promisolow from the Robert N. Butler Colombia Aging Center will discuss the study he leads: “The Dog Aging Project”.
The domestic dog is one of the most phenotypically diverse species in the world. This diversity is seen not only in widely recognized features such as size, coat color, or behavior, but also in lifespan and age-related disease risk.
To understand how genetic and environmental factors shape this variation in aging and age-related disease, a large team of US-based investigators has launched the Dog Aging Project (dogagingproject.org), a nationwide, citizen science-based long-term longitudinal study in tens of thousands of companion dogs, including all ages and all breeds.
Studying many thousands of dogs over their lifetime, the project will collect a diversity of information about each dog, including function and frailty, genetics, electronic health records, extensive survey information and environmental data. For a subset of the dogs, we will also have real-time actigraphy measures, and annual measures of the metabolome, epigenome, and microbiome. A smaller subset of these dogs will be enrolled in a randomized clinical trial to test the ability of low-dose rapamycin to increase healthspan in dogs.
The Dog Aging Project is an Open Data project. We will make the data available to researchers around the world, and we will encourage interested researchers to develop collaborative proposals to extend the breadth and depth of research carried out in this unique cohort.